O-Desmethyl Midostaurin, CAS No. 740816-86-8, is a biochemical

Product information

CAS Number: 740816-86-8

Molecular Weight: 556.61

Formula: C34H28N4O4

Synonym:

CGP62221

O-Desmethyl PKC412

Chemical Name: O-Desmethyl Midostaurin

Smiles: CN([C@@H]1C[C@H]2O[C@@](C)([C@@H]1O)N1C3=C4C(=C5C(CNC5=O)=C3C3=CC=CC=C13)C1=CC=CC=C1N42)C(=O)C1C=CC=CC=1

InChiKey: PXOCRDZEEXVZQC-AFUPZKSLSA-N

InChi: InChI=1S/C34H28N4O4/c1-34-31(39)24(36(2)33(41)18-10-4-3-5-11-18)16-25(42-34)37-22-14-8-6-12-19(22)27-28-21(17-35-32(28)40)26-20-13-7-9-15-23(20)38(34)30(26)29(27)37/h3-15,24-25,31,39H,16-17H2,1-2H3,(H,35,40)/t24-,25-,31-,34+/m1/s1

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

1. Levis M, et al. Plasma inhibitory activity (PIA): a pharmacodynamic assay reveals insights into the basis for cytotoxic response to FLT3 inhibitors.Blood. 2006 Nov 15;108(10):3477-83.

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